Inter have sacked manager Frank de Boar after just 14 games in charge.
The Dutchman replaced Roberto Mancini over the summer, but has lost seven games already this season.
In a statement the club said, “FC Internazionale announce today that they have parted company with Frank de Boer,” a statement announced.
“Inter Primavera Coach Stefano Vecchi will take temporary charge of the first team for Thursday’s UEFA Europa League match against Southampton.
“Inter would like to place on record our thanks to Frank and his coaching team for their work with the club over the past few months, and we wish them the best for the future.
“Further announcements regarding the first team Coaching position will be made in due course.”