Balzan face highflying Marsaxlokk in the Friday night early kick-off.
A win for M’lokk would lift them to top spot for tonight at least.
Friday’s second game is between Sliema Wanderers and Hibernians.
Sliema are handily placed in third place and on paper look favourite to take all three points against a Hibs side who have gone off the boil in recent games.